SiliCycle is the leader in the development of functionalized silica gels, gathered under the name SiliaBond, for use in organic synthesis. The backbone of all SiliaBond products is SiliCycle SiliaFlash® F60 which provides superior performance for all types of applications due to the narrow particle size distribution and high purity. All the products in this section are made of standard flash silica gel, namely 40-63µm, 60A. SiliCycle is able to provide all functionalized products on any silica of this catalog (SiliaFlash, IMPAQ™, SiliaSphere™ and SiliaSphere™ PC) in any format (SiliaPrep™ SPE and SiliaSep™, SiliaSep, etc.) on a custom basis.
The use of solid supported reagents and scavengers is an excellent way to expedite organic synthesis by simplifying the purification process. Standard purification procedures including chromatography, liquid-liquid extraction, and crystallization can be time-consuming and difficult to scale up. In many cases, supported reagents have distinct advantages over their solution-phase counterparts, the biggest one being the ability to do multiple transformations in a single pot, the immobilization of toxic reagents, and increased selectivity. They are suitable for use in batch reactions and in flow through applications.
- Extremely easy product / API isolation and purification (simple & quick filtration of the heterogeneous support)
- Eliminates or strongly reduces the need for laborious purifications
- No leaching of silica or catalyst and no cross contamination
- Highly suitable for either batch or continuous flow applications
- Convenient for high throughput medicinal & discovery chemistry
- Improved reactivity & selectivity over homogeneous reagents / catalyst
- Compares very favourably to polymer-based reagents: no swelling, thermally stable, more easily scalabe, faster kinetics, compatible with all solvents and mechanically stable.
SiliCycle’s SiliaMetS Metal Scavengers are functionalized silica gels designed to react and bind excess metal complexes. In recent years, the time pressure associated with quickly bringing candidate drugs to market has increased the number of transition metal-catalyzed reactions being transferred from lead optimization to early scale-up. The removal of post-reactions metal residues has become a major issue in the pharmaceutical industry. Purification of APIs from residual metal catalyst by traditional methods (chromatography, activated carbon, distillation, etc.) often leads to problems such as high costs, time loss, low efficiency, and reduced API yields. To overcome these limitations, SiliCycle has developed SiliaMetS Metal Scavengers, a range of products that have significantly changed how chemists can purify APIs.
Product | Description | Category | Quote Cart |
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Bond Elut-Si, 200Mg 3ml, 50p |
Functionalized |
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Bond Elut-Si, 500Mg 6ml,30p |
Functionalized |
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Bond Elut-CBA, 500Mg 6ml,30p |
Functionalized |
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Bond Elut-SCX, 500Mg 6ml,30p |
Functionalized |
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Bond Elut-Si Acid Wash, 500Mg 3ml, 50p |
Functionalized |
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Bond Elut-SCX, 300Mg 3ml, 50p |
Functionalized |
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Bond Elut-DEA, 200Mg 3ml, 50p |
Functionalized |
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Bond Elut-C8, 500Mg 6ml,30p |
Functionalized |
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Bond Elut-Certify, 300Mg 6ml,30p |
Functionalized |
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Bond Elut-SCX, 500Mg/SiOH 500 6ml,30p |
Functionalized |
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Bond Elut-SCX, 200Mg 3ml, 50p |
Functionalized |
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BOND ELUT-CERTIFY II, 100MG 1CC, 100p |
Functionalized |
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Bond Elut 1cc LRC-C18, 115Mg, 50p |
Functionalized |
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Bond Elut LRC-C18 OH, 200Mg, 50p |
Functionalized |
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Bond Elut LRC-Si Acid Wash, 500Mg, 50p |
Functionalized |
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Bond Elut LRC-NH2, 500Mg, 50p |
Functionalized |
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Bond Elut-Certify, 50Mg 1ml, 100p |
Functionalized |
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Bond Elut C18, 100mg 1ml, 100p |
Functionalized |
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Bond Elut-C8, 100mg 1mL, 100p |
Functionalized |
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Bond Elut-C2, 100mg 1mL, 100p |
Functionalized |
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Bond Elut-C1, 100mg 1mL, 100p |
Functionalized |
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Bond Elut-PH, 100mg 1mL, 100p |
Functionalized |
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Bond Elut-CH, 100mg 1mL, 100p |
Functionalized |
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Bond Elut-CN-E, 100mg 1mL, 100p |
Functionalized |
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Bond Elut-CN-E, 100Mg 1ml-Tabless 100p |
Functionalized |
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Bond Elut-CN-U, 100Mg 1ml, 100p |
Functionalized |
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Bond Elut-2OH, 100mg 1mL, 100p |
Functionalized |
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Bond Elut SI, 100mg 1ml, 100p |
Functionalized |
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Bond Elut-Si, Ewp- 100Mg 1ml, 100p |
Functionalized |
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Bond Elut CBA, 100mg 1ml, 100p |
Functionalized |
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Bond Elut-PRS, 100mg 1mL, 100p |
Functionalized |
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Bond Elut SCX, 100mg 1ml, 100p |
Functionalized |
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Bond Elut NH2, 100mg 1ml, 100p |
Functionalized |
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Bond Elut-PSA, 100mg 1mL, 100p |
Functionalized |
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Bond Elut-DEA, 100mg 1mL, 100p |
Functionalized |
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Bond Elut SAX, 100mg 1ml, 100p |
Functionalized |
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BOND ELUT SAX, 100MG 1ML TABLESS, 100p |
Functionalized |
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BOND ELUT SAX, 100MG 1ML TABLESS, 500p |
Functionalized |
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Bond Elut-PBA, 100mg 1mL, 20p |
Functionalized |
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Bond Elut PBA, 100mg 1ml, 100p |
Functionalized |
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Bond Elut-C18 OH, 100mg 1mL, 100p |
Functionalized |
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Bond Elut-Al-B, 100Mg 1ml, 100p |
Functionalized |
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Bond Elut-AL-N, 100mg 1mL, 100p |
Functionalized |
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BOND ELUT-FL, 100MG 1ML, 100p |
Functionalized |
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Bond Elut-C18, 200mg 3ml, 50p |
Functionalized |
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Bond Elut-C18, 200Mg 3ml, Tabless 50p |
Functionalized |
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Bond Elut-C8, 200mg 3mL, 50p |
Functionalized |
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Bond Elut-C2, 200mg 3mL, 50p |
Functionalized |
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Bond Elut C18, 500mg 3ml, 50p |
Functionalized |
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Bond Elut-C8, 500mg 3mL, 50p |
Functionalized |
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Bond Elut-C2, 500mg 3mL, 50p |
Functionalized |
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Bond Elut-C1, 500mg 3mL, 50p |
Functionalized |
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Bond Elut-PH, 500mg 3mL, 50p |
Functionalized |
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Bond Elut-CH, 500mg 3mL, 50p |
Functionalized |
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Bond Elut-CN-E, 500mg 3mL, 50p |
Functionalized |
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Bond Elut-2OH, 500mg 3mL, 50p |
Functionalized |
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Bond Elut SI, 500mg 3ml, 50p |
Functionalized |
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Bond Elut CBA, 500mg 3ml, 50p |
Functionalized |
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Bond Elut PRS, 500mg 3ml, 50p |
Functionalized |
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Bond Elut-SCX, 500mg 3ml, 50p |
Functionalized |
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Bond Elut NH2, 500mg 3ml, 50p |
Functionalized |
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Bond Elut-PSA, 500mg 3ml, 50p |
Functionalized |
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Bond Elut-DEA, 500mg 3mL, 50p |
Functionalized |
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Bond Elut SAX, 500mg 3ml, 50p |
Functionalized |
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Bond Elut-SAX, 500Mg 3ml-Tabless, 50p |
Functionalized |
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Bond Elut-C18 OH, 500mg 3mL, 50p |
Functionalized |
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Bond Elut-AL-A, 500mg 3mL, 50p |
Functionalized |
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Bond Elut-AL-B, 500mg 3mL, 50p |
Functionalized |
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Bond Elut-AL-N, 500mg 3mL, 50p |
Functionalized |
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Bond Elut Fl, 500mg 3ml, 50p |
Functionalized |
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Bond Elut Certify, 130mg 3ml, 50p |
Functionalized |
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BOND ELUT CERTIFY 130MG,3ML TABLESS,50P |
Functionalized |
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Bond Elut C18, 500mg 6ml,30p |
Functionalized |
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Bond Elut-C18, 500Mg 6ml Tabless,30p |
Functionalized |
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Bond Elut-C8, 500mg 6mL,30p |
Functionalized |
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Bond Elut C18, 50mg 1ml, 100p |
Functionalized |
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Bond Elut-C18, 50Mg 1ml, 500p |
Functionalized |
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Bond Elut-C8, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-C2, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-PH, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-CN-E, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-C18 OH, 50Mg 1ml, 100p |
Functionalized |
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Bond Elut-CN-U, 50Mg 1ml, 100p |
Functionalized |
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Bond Elut-2OH, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-SI, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-AL-A, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-Al-B, 50Mg 1ml, 100p |
Functionalized |
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Bond Elut-Al-N, 50Mg 1ml, 100p |
Functionalized |
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Bond Elut-Fl, 50Mg 1ml, 100p |
Functionalized |
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Bond Elut-CBA, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-PRS, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-SCX, 50mg 1mL, 100p |
Functionalized |
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Bond Elut NH2, 50mg 1ml, 100p |
Functionalized |
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Bond Elut-PSA, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-DEA, 50mg 1mL, 100p |
Functionalized |
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Bond Elut-SAX, 50mg 1mL, 100p |
Functionalized |
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Bond Elut Certify II, 200mg 3ml, 50p |
Functionalized |
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Bond Elut Certify, 300mg 3ml, 50p |
Functionalized |
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BOND ELUT-CERTIFY,300MG 3ML,TABLESS 50P |
Functionalized |
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Bond Elut Certify, 300mg 6ml,30p |
Functionalized |
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