Silica Shapes and Sizes

Selecting the Best Silica: Particle Shape and Size, Pore Diameter

|||Silica Shapes and Sizes
Silica Shapes and Sizes2019-01-22T16:20:55+00:00

The quality of a silica gel is extremely important when you are using it for chromatography purposes, particularly when dealing with difficult separations of valuable compounds. You need to be confident about your recoveries. In chromatography, there are at least three physical properties that will influence your separation and that you need to consider when choosing your silica gel:

  • Particle shape (irregular or spherical )
  • Particle size distribution (tight or large)
  • Pore diameter (surface area)

These characteristics will directly influence crucial parameters involved in a successful chromatography:

  • Resolution (efficiency of separation & final purity)
  • Retention (which allows separation)
  • Capacity (maximal sample quantity and final recovery/yield)
  • Back-pressure (speed and pumps related issues)

Various pore sizes are available in a wide range of particle sizes (20 to 200um).

Irregular silica gels are traditional in flash or gravity chromatography and have always been a spontaneous choice for preparative chromatography. Nowadays, spherical particles are now used increasingly. Cost is very important in preparative and process chromatography, and the use of monodisperse spherical particles with narrow particle size distribution is more expensive. It is possible in this case to use irregular silica but the separation may not provide the desired results. For these situations, There’s a more affordable class of spherical particles for preparative chromatography: SiliaSphere PC.

The advantage of using spherical materials over standard irregular material includes the following:

  • Increased efficiency of the eluent’s flow characteristics
  • Better resolution
  • Ease of packing
  • Very high specific surface area
  • High mechanical stability under higher pressures

The selection of the particle size distribution and pore diameter for your application varies on the type of chromatography being done. In addition, not all the 40-63um gels are the same, i.e the absence of so-called fines (particles below 40um) has a great impact on performance.

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Below a series of productcodes for spherical and irregular silica gels are listed  – as well as more specific products from out catalog. Please note that availability of certain silica gels may vary in time. Via the Product Search or Product Category all website listed products can be retrieved. In case of any specific needs or questions, please Contact Us.

Spherical Silica

Product NumberParticle Size (um)Particle Size (mesh)Pore Diameter (A)
S10030B-A5030060
S10072B-A6025060
S10034B-A7520060
S10040B-A10015060
S10063B-A15010060
S10066B-A2007060
S10068B-A3005060
S10020C20-4570
S10040C75-20070-20070
S10030C200-37545-7070
S10070C200-50035-7070
S10095D-A2590
S10095E-A20100
S10020E20-45100
S10030E40-75200-400100
S10040E75-20070-200100
S10065E150-25060-100100
S10070E200-50035-70100
S10009G-A20120
S10030G-A50300120
S10034G-A75200120
S10040G-A100150120
S10063G-A150100120
S10020M20-45300
S10030M40-75200-400300
S10040M75-20070-200300
S10064M150-20070-200300
S10070M200-50035-70300
S10020P20-45500
S10030P40-75200-400500
S10040P75-20070-200500
S10070P200-50035-70500
S10020S20-45800
S10030S40-75200-400800
S10040S75-20070-200800
S10070S200-50035-70800
S10020T20-451000
S10030T40-75200-4001000
S10040T75-20070-2001000
S10070T200-50035-701000

Irregular Silica

Product NumberParticle Size (um)Particle Size (mesh)Pore Diameter (A)
R10037L75-150100-20030
R10130A40-63230-40040
R10150A60-120325-62540
R10140A60-20070-25040
R10160A120-20070-12540
R10180A500-100018-3540
R10110B0-2060
R10014B5-20625-250060
R10023B20-4560
R10030B (F60)40-63230-40060
R12030B (P60)40-63230-40060
R10530B (acid washed)40-63230-40060
R10150B60-120325-62560
R10040B (G60)60-20070-23060
R10140B (GE60)60-20070-23060
R10137B75-150100-20060
R10057B105-17586-14060
R10160B120-20070-12560
R10170B200-50035-7060
R10180B500-100018-3560
R10130D40-63230-40090
R10140D60-20070-25090
R10157D105-17586-14090
R10170D200-50035-7090
R10180D500-100018-3590
R10181D800-120016-2290
R10130H40-63230-400150
R10150H60-120325-625150
R10140H60-20070-250150
R10157H105-17586-140150
R10160H120-20070-125150
R10170H200-50035-70150
R10172H250-50035-60150
R10180H500-100018-35150
R10181H800-120016-22150
R10130M40-63230-400300
R10140M60-20070-250300
R10170M200-50035-70300

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