Syringe filters are available with the following membranes: Nylon, MCE, Polyethersulfone, Polypropylene, PTFE, PVDF and Regenerated Cellulose. Porosities range from 0.1 µm – 10 µm, available filter diameters range from 4 mm (up to 2 ml sample volume) up to 30 mm (up to approx. 200 ml sample volume). Adapted with luer-lock in order to prevent filter blow-off. The membrane & porosity is imprinted on filter housing for certain identification.
Depending on your sample volume, the table below shows the recommendations.
| Sample Volume | Sample Loss | Filter Diameter |
|---|---|---|
| up to 2 ml | < 7.5 uL | 4 mm |
| up to 10 ml | < 25 uL | 13 mm |
| up to 100 ml | < 50 uL | 25 mm |
| up to 200 ml | < 137 uL | 33 mm |
The guideline below supports the initial choices to be made regarding pore size and membrane type.
| Type | Description | Application |
|---|---|---|
| CA, CA GFPF, CA PPPF | Cellulose Acetate | Proteins in aqueous samples, aqueous samples, olygomeres, polymeres, biological macromolecules |
| GF | Glass Fiber | Heavily contaminated samples |
| MCE, MCE GFPF, MCE PPPF | Mixed Cellulose Ester (CA/CN) | Hydrophilic for aqeous and polar solutions |
| Nylon, Nylon GFPF, Nylon PPPF | Nylon | Low extractables, mechanically strong up to 50°C |
| PES, PES GFPF, PES PPPF | Polyethersulphone | Hydrophilic, very low protein binding. Ion chromatography, high heat resistance |
| PP | Polypropylene | Hydrophilic, high chemical resistance, low protein binder for use in strong acids and bases |
| Hydrophobe (regular) PTFE, PTFE GFPF, PTFE PPPF | Polytetrafluoroethylene | Hydrophobic, very low extractables, very high chemical resistance, very high thermal stability, Gasfiltration |
| Hydrophile (special) PTFE Hydrophil, PTFE Hydrophil GFPF, PTFE Hydrophil PPPF | Surface treated PTFE for hydrophile samples | Hydrophilic, very low extractables, very high chemical resistance, very high thermal stability |
| (regular) PVDF, PVDF GFPF, PVDF PPPF | Polyvinylidene difluoride | Low hydrophilic, low protein binder, broad chemical compability |
| Hydrophile (special) PVDF Hydrophil , PVDF Hydrophil GFPF, PVDF Hydrophil PPPF | Surface treated PVDF for hydrophile samples | Hydrophilic, low protein binder, broad chemical compability |
| RC, RC GFPF, RC PPPF | Regenerated Cellulose | Hydrophilic solvent resistant, very low protein binder |
The table below illustrated the compability of the filter membranes with different solvents.
(Y = compatible, L = limited compatible, X = not compatible)
(Y = compatible, L = limited compatible, X = not compatible)
| Solvent type | Solvent | Cellulose Acetate | Glass Fiber | mix. Cellulose Ester | Nylon | PES | PP | PTFE | Hydrophile PTFE | PVDF | Hydrophile PVDF | Regen. Celluose |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acid | Acetic, 25% | L | Y | X | L | Y | Y | Y | Y | Y | Y | L |
| Acid | Acetic, Glacial (100%) | X | Y | X | L | Y | Y | Y | Y | Y | Y | X |
| Acid | Ethanolic acid (Oxalic acid), 10% | L | Y | L | X | L | Y | Y | Y | Y | Y | L |
| Acid | Formic, 100% | X | Y | L | X | Y | Y | Y | Y | Y | Y | L |
| Acid | Formic, 25% | L | Y | L | X | Y | Y | Y | Y | Y | Y | L |
| Acid | Hydrochloric, 25% | X | Y | X | X | Y | Y | Y | Y | Y | Y | X |
| Acid | Hydrochloric, Concentrated | X | Y | X | X | Y | Y | Y | Y | Y | Y | X |
| Acid | Nitric, 25% | X | Y | X | X | Y | Y | Y | Y | Y | Y | X |
| Acid | Nitric, Concentrated | X | Y | X | X | X | L | L | L | L | L | X |
| Acid | Phosphoric, 25% | L | Y | L | X | L | Y | Y | Y | Y | Y | L |
| Acid | Phosphoric, 80% | L | Y | X | X | L | Y | Y | Y | L | L | L |
| Acid | Sulphuric, 25% | X | Y | X | X | Y | Y | Y | Y | Y | Y | L |
| Acid | Sulphuric, Concentrated | X | Y | X | X | X | Y | Y | Y | X | X | X |
| Acid | Trichloroacetic, 25% | Y | Y | L | X | L | Y | Y | Y | L | L | Y |
| Alcohol | Amyl Alcohol | Y | Y | L | Y | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | Benzyl Alcohol | L | L | L | Y | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | Butanol | Y | Y | L | Y | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | Ethanol, 70% | Y | Y | Y | L | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | Ethanol, 98% | Y | Y | L | Y | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | Ethylene Glycol | Y | Y | L | Y | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | Glycerol | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | i-Propanol | Y | Y | L | Y | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | Isopropanol | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | Methanol, 98% | Y | Y | X | Y | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | n-Propanol | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y |
| Alcohol | Propylene Glycol | L | Y | L | Y | Y | Y | Y | Y | Y | Y | Y |
| Aldehydes | Acetaldehyde | X | Y | X | L | Y | L | Y | Y | Y | Y | Y |
| Aldehydes | Formaldehyde Solution 10% | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y | L |
| Amides | Acetonitrile | X | Y | X | Y | L | Y | Y | Y | Y | Y | Y |
| Amides | Aniline | X | Y | X | Y | L | Y | Y | Y | L | L | Y |
| Amides | Diethylacetamide | X | Y | X | Y | L | Y | Y | Y | L | L | Y |
| Amides | Dimethyl Formamide (DMF) | X | Y | X | Y | X | Y | Y | Y | X | X | L |
| Amides | Pyridine | X | Y | X | Y | X | Y | Y | Y | Y | Y | Y |
| Amides | Triethanolamine | Y | Y | L | Y | L | Y | Y | Y | L | L | Y |
| Amides | Urea | Y | Y | Y | Y | L | Y | Y | Y | Y | Y | Y |
| Base | Ammonium Hydroxide, 25% | L | Y | X | L | Y | Y | Y | Y | L | L | L |
| Base | Potasium Hydroxide, 1 mol/l | X | L | X | Y | Y | Y | Y | Y | L | L | L |
| Base | Sodium Hydroxide, 1 mol/l | X | L | X | Y | Y | Y | Y | Y | Y | Y | L |
| Base | Sodium Hydroxide, 25% | X | L | X | Y | Y | Y | Y | Y | Y | Y | L |
| Esters | 2-Ethoxyethyl Acetate | L | Y | X | Y | X | Y | Y | Y | X | X | Y |
| Esters | Amyl & Butyl Acetate | L | Y | X | Y | X | L | Y | Y | X | X | Y |
| Esters | Benzyl Benzoate | Y | Y | X | Y | X | Y | Y | Y | L | L | Y |
| Esters | Ethyl & Methyl Acetate | X | Y | X | Y | X | L | Y | Y | Y | Y | Y |
| Esters | Isopropyl Myristate | Y | Y | X | Y | X | Y | Y | Y | L | L | Y |
| Esters | Methyl Cellosolve Acetate | X | Y | X | Y | X | Y | Y | Y | L | L | Y |
| Esters | Propyl Acetate | L | Y | X | Y | X | L | Y | Y | X | X | Y |
| Esters | Propylene Glycol Acetate | X | Y | X | Y | X | Y | Y | Y | L | L | Y |
| Esters | Tricresyl Phosphate | Y | Y | X | Y | X | Y | Y | Y | L | L | Y |
| Ethers, Oxides | Dimethylsulfoxide (DMSO) | X | Y | X | Y | X | X | Y | Y | X | X | Y |
| Ethers, Oxides | Dioxane | X | Y | X | Y | X | Y | Y | Y | L | L | Y |
| Ethers, Oxides | Ethyl Ether | Y | Y | L | Y | Y | L | Y | Y | Y | Y | Y |
| Ethers, Oxides | Isopropyl Ether | Y | Y | X | Y | Y | Y | Y | Y | Y | Y | Y |
| Ethers, Oxides | Tretrahydrofuran (THF) | X | Y | X | L | X | L | Y | Y | L | L | Y |
| Ethers, Oxides | Triethanolamine | Y | Y | L | Y | L | Y | Y | Y | L | L | Y |
| Ethers, Oxides | Water | Y | Y | Y | Y | Y | Y | X | Y | L | Y | Y |
| Halogenated Hydrocarbon | Carbon Tetrachloride | L | Y | Y | Y | X | L | Y | Y | Y | Y | Y |
| Halogenated Hydrocarbon | Chloroform | X | Y | Y | L | X | L | Y | Y | Y | Y | Y |
| Halogenated Hydrocarbon | Dichloromethane | X | Y | Y | L | X | L | Y | Y | Y | Y | Y |
| Halogenated Hydrocarbon | Freon | Y | Y | Y | Y | L | Y | Y | Y | Y | Y | Y |
| Halogenated Hydrocarbon | Methylene Chloride | X | Y | X | L | X | L | Y | Y | Y | Y | Y |
| Halogenated Hydrocarbon | Monochlorobenzene | Y | Y | X | Y | L | Y | Y | Y | Y | Y | Y |
| Halogenated Hydrocarbon | Trichloroethylene | Y | Y | Y | Y | X | L | Y | Y | Y | Y | Y |
| Hydrocarbon | Benzene | Y | Y | Y | Y | X | L | Y | Y | Y | Y | Y |
| Hydrocarbon | Cyclohexane | Y | Y | Y | Y | X | L | Y | Y | Y | Y | Y |
| Hydrocarbon | Hexane, Xylene | Y | Y | Y | Y | X | L | Y | Y | Y | Y | Y |
| Hydrocarbon | Kerosene, Gasoline | Y | Y | Y | Y | L | L | Y | Y | Y | Y | Y |
| Hydrocarbon | Petroleum ether | Y | Y | Y | Y | Y | L | Y | Y | Y | Y | Y |
| Hydrocarbon | Tetralin, Decalin | Y | Y | X | y | y | L | Y | Y | Y | Y | Y |
| Hydrocarbon | Toluene | L | Y | Y | Y | X | L | Y | Y | Y | Y | Y |
| Hydrocarbon | Xylene | Y | Y | Y | Y | X | L | Y | Y | L | L | Y |
| Ketone | Acetone | X | Y | X | Y | X | Y | Y | Y | X | X | Y |
| Ketone | Cyclohexanone | X | Y | X | Y | X | Y | Y | Y | X | X | Y |
| Ketone | Isopropylacetone | Y | Y | X | Y | X | Y | Y | Y | X | X | Y |
| Ketone | Methyl Ethyl Ketone | L | Y | X | Y | X | L | Y | Y | L | L | Y |
| Ketone | Methyl Isobutyl Ketone | L | Y | X | Y | X | L | Y | Y | L | L | Y |
| Misc | Hydrogen Peroxide, 30% | Y | Y | Y | Y | L | Y | Y | Y | L | L | Y |
| Misc | Phenol, Aqueous, 10% | X | Y | Y | L | X | Y | Y | Y | L | L | X |
| Misc | Silicone Oil, Mineral Oil | Y | Y | Y | L | Y | Y | Y | Y | Y | Y | Y |
-
Filter, Disk, PETE, 8.0um, 47mm, 100p -
Titan2 HPLC PTFE Filter Yellow, 0.45um, 17mm, 500pack
-
Syringeles filter vial, 0.45 um, Nylon, Blue, 100p
-
SF Polyvinylidene Fluoride (PVDF), 13mm, 0.20um, 100/box
-
SF Polyvinylidene Fluoride (PVDF), 13mm, 0.20um, 500/box
-
SyringeFilter,25mm PES 0.20um, Sterile, 100x
-
Yeti CA Syringe Filters, 0.22um, 13mm, 100p
-
Yeti CA Syringe Filters, 0.45um, 25mm, 100p
-
Yeti CA Syringe Filters, 0.45um, 30mm, 50p
-
Yeti Nylon Syringe Filters, 0.22um, 13mm, 100p
-
Yeti Nylon Syringe Filters, 0.22um, 25mm, 100p
-
Yeti PES Syringe Filters, 0.22um, 13mm, 100p
-
Yeti PP Syringe Filters, 0.22um, 4mm, 200p
-
Yeti PP Syringe Filters, 0.22um, 13mm, 100p
-
Yeti PP Syringe Filters, 0.45um, 13mm, 100p
-
Yeti PP Syringe Filters, 0.45um, 25mm, 100p
-
Yeti Hydrophilic PTFE Syringe Filters, 0.22um, 4mm, 200p
-
Yeti Hydrophilic PTFE Syringe Filters, 0.45um, 4mm, 200p
-
Yeti Hydrophobic PTFE Syringe Filters, 0.22um, 13mm, 100p
-
Yeti Hydrophilic PTFE Syringe Filters, 0.22um, 13mm, 100p